Hyperhidrosis, An Issue of Dermatologic Clinics, 1e (The Clinics: Dermatology)
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Topics in this issue of Dermatologic Clinics include: Incidence and prevalence; Impact on quality of life; Special considerations of hyperhidrosis in children; Topical therapies; Iontophoresis; Botox for axillary hyperhidrosis; Botox for palmar/plantar hyperhidrosis; Botox for other hyperhidrosis; Systemic therapies for hyperhidrosis; Procedural approaches; Endoscopic thoracic sympathectomy; Emerging and investigative treatments; Resources for patients and physicians; Incorporating diagnosis and treatment into clinical practice. Dr David Pariser is Editor of this publication; a founding member of the International Hyperhidrosis Society and renown researcher and lecturer on mechanism, diagnosis, and treatment of hyperhidrosis, Dr Pariser continues to investigate therapies that are effective for patients.
Texas Health Science Center at Houston, Houston, Texas LISA J. PIERETTI, MBA Executive Director and Founding Member, International Hyperhidrosis Society, Quakertown, Pennsylvania iv Contributors NOWELL SOLISH, MD, FRCPC Division of Dermatology, Women’s College Hospital, University of Toronto, Toronto, Ontario, Canada OLUSHOLA AKINSHEMOYIN VAUGHN, BA Student, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin ADA REGINA TRINDADE DE ALMEIDA, MD
initial treatment of palmar and axillary hyperhidrosis. J Vasc Surg 2012;55:1696–700. 36. Wolosker N, Krutman M, Campdell TP, et al. Oxybutynin treatment for hyperhidrosis: a comparative analysis between genders. Einstein (Sao Paulo) 2012;10:405–8. Impact of Hyperhidrosis 37. Wolosker N, Krutman M, Kauffman P, et al. Effectiveness of oxybutynin for treatment of hyperhidrosis in overweight and obese patients. Rev Assoc Med Bras 2013;59:143–7. 38. Wolosker N, Schvartsman C, Krutman M, et al.
groin, and less common areas like the submammary region and gluteal cleft, are discussed. Frey syndrome, compensatory sweating, and postamputation stump hyperhidrosis are also discussed. PATIENT EVALUATION OVERVIEW A thorough HH history and review of symptoms should be obtained from the patient, including age of onset of HH, location and symmetry of sweating, aggravating/alleviating factors, prior treatments for HH, family history of HH, and current medications that may exacerbate the
sweating following thoracoscopic sympathectomy. Int J Surg 2011; 9(5):437–9. 29. Deng B, Tan QY, Jiang YG, et al. Optimization of sympathectomy to treat palmar hyperhidrosis: the systematic review and meta-analysis of studies published during the past decade. Surg Endosc 2010; 25(6):1893–901. 30. Kim WO, Kil HK, Yoon KB, et al. Botulinum toxin: a treatment for compensatory hyperhidrosis in the trunk. Dermatol Surg 2009;35(5):833–8. 31. Findikcioglu A, Kilic D, Hatipoglu A. Is clipping superior to
urinary difficulty, GI complaints, headache, and lassitude, although 30% had to discontinue therapy because of side effects. Therapy seems to work well in men and women, and overweight and obese individuals.10,11 There are no guidelines to use when choosing which anticholinergic drug to use for HH. Because of the more limited penetration into the central nervous system, glycopyrrolate is a good option. Patients may respond to one anticholinergic drug better than another, or may experience fewer